The Syncytin-1 (HERV) Antibody from Abbexa Ltd is a Rabbit Polyclonal antibody to ERVW-1. This antibody recognizes Homo Sapiens, and Human antigen. The Syncytin-1 (HERV) Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer